Opportunity Information: Apply for W81XWH 20 OPORP CTA
The DoD Orthotics and Prosthetics Outcomes, Clinical Trial Award (FY20 OPORP CTA) is a Department of Defense research funding opportunity designed to move orthotics and prosthetics research into real-world clinical testing, with the goal of producing evidence that can directly improve care. The program is focused on clinical trials that could meaningfully improve the health, function, and overall well-being of Service members, Veterans, and other people living with limb loss or limb impairment. Rather than supporting early-stage concept development alone, this mechanism is aimed at implementing trials that test orthoses and/or prostheses in people and generate results that clinicians, health systems, and decision-makers can use.
A defining feature of this award is its emphasis on patient-centric outcomes. Projects are expected to evaluate orthotic and prosthetic devices using outcomes that matter to patients and everyday clinical decision-making, such as functional mobility, comfort, usability, pain, quality of life, participation in daily activities, satisfaction, and other clinically meaningful measures. The underlying intent is to produce clinically useful evidence that helps optimize device selection, fitting, training, and broader rehabilitation strategies, ultimately improving patient outcomes in practical, measurable ways.
The opportunity supports a wide range of trial sizes and maturity levels. Applicants may propose smaller proof-of-concept studies that demonstrate feasibility or generate data to shape the design of a larger definitive trial, as well as larger-scale trials conducted in relevant patient populations. The program also signals strong interest in alternative, real-world-oriented research designs, including pragmatic trials and practice-based evidence studies. These designs are meant to reflect how care is actually delivered in clinical settings, making the findings more readily translatable to routine practice and more informative for clinical guidelines or policy decisions. In other words, the DoD is not only looking for tightly controlled experiments, but also for evidence that can support adoption and implementation of effective devices and approaches in everyday healthcare environments.
Administratively, this opportunity was offered by the Department of Defense, Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA). The funding opportunity number is W81XWH-20-OPORP-CTA, listed under CFDA 12.420, and categorized as discretionary funding under science and technology and other research and development. Funding instruments available include grants and cooperative agreements, meaning some awards may involve a more collaborative relationship with the government than a standard grant, depending on the specific terms.
Eligibility is listed as unrestricted, indicating that a broad range of organizations could apply, subject to any additional eligibility language in the full announcement. The posting listed an expected number of awards of four. The original opportunity timeline shows a creation date of March 30, 2020, with an original closing date of July 29, 2020. The posted award ceiling is shown as 0, which typically indicates that the ceiling was not specified in that data field and would need to be confirmed in the full funding announcement or accompanying program guidance.
Overall, the OPORP Clinical Trial Award is geared toward generating high-value clinical evidence on orthotic and prosthetic interventions, prioritizing outcomes that reflect patient experience and real clinical impact, and encouraging study designs that help translate successful technologies and practices into standard care for individuals affected by limb loss or impairment.Apply for W81XWH 20 OPORP CTA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Orthotics and Prosthetics Outcomes, Clinical Trial Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Mar 30, 2020.
- Applicants must submit their applications by Jul 29, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: DoD Orthotics and Prosthetics Outcomes, Clinical Trial Award (FY20 OPORP CTA)
What is the FY20 OPORP Clinical Trial Award (CTA)?
The DoD Orthotics and Prosthetics Outcomes, Clinical Trial Award (FY20 OPORP CTA) is a Department of Defense research funding opportunity intended to move orthotics and prosthetics research into real-world clinical testing. The goal is to generate clinical evidence that can be used to directly improve care.
What is the main purpose of this funding opportunity?
The main purpose is to support clinical trials that test orthoses and/or prostheses in people and produce results that clinicians, health systems, and decision-makers can use in everyday care. It is focused on generating clinically useful evidence rather than supporting early-stage concept development alone.
Who is this program intended to benefit?
The program is focused on improving the health, function, and overall well-being of Service members, Veterans, and other people living with limb loss or limb impairment.
What types of studies are supported under this award?
The award supports clinical trials evaluating orthotic and/or prosthetic devices in human participants. It supports a range of trial sizes and maturity levels, including smaller proof-of-concept studies and larger-scale trials in relevant patient populations.
Does this award support early-stage device concept development?
Based on the description provided, this mechanism is aimed at implementing trials that test devices in people and generate clinically actionable evidence, rather than supporting early-stage concept development alone.
What does "patient-centric outcomes" mean in the context of this award?
This award emphasizes outcomes that matter to patients and routine clinical decision-making. Examples include functional mobility, comfort, usability, pain, quality of life, participation in daily activities, satisfaction, and other clinically meaningful measures.
What kinds of outcomes are applicants expected to measure?
Projects are expected to evaluate orthotic and prosthetic devices using clinically meaningful, patient-relevant outcomes such as functional mobility, comfort, usability, pain, quality of life, participation in daily activities, satisfaction, and similar measures that reflect real clinical impact.
Are pragmatic trials or real-world study designs encouraged?
Yes. The program signals strong interest in alternative, real-world-oriented research designs, including pragmatic trials and practice-based evidence studies, to reflect how care is actually delivered in clinical settings.
Why does the program emphasize pragmatic trials and practice-based evidence?
These designs are intended to make findings more translatable to routine practice and more informative for clinical guidelines or policy decisions by reflecting real clinical environments rather than only tightly controlled experimental conditions.
Is the DoD only looking for tightly controlled clinical trials?
No. While clinical trials are central to the award, the description indicates the DoD is also interested in real-world evidence approaches that can support adoption and implementation in everyday healthcare environments.
What kinds of devices or interventions are in scope?
Clinical trials that test orthoses and/or prostheses in people are in scope. The focus is on generating evidence that can optimize device selection, fitting, training, and broader rehabilitation strategies.
How are the results expected to be used?
The intent is to produce clinically useful evidence that can help optimize device selection, fitting, training, and rehabilitation strategies, and that can be used by clinicians, health systems, and decision-makers in real-world practice.
Which government organization offered this opportunity?
This opportunity was offered by the Department of Defense, Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA).
What is the funding opportunity number?
The funding opportunity number is W81XWH-20-OPORP-CTA.
What CFDA number is associated with this opportunity?
The opportunity is listed under CFDA 12.420.
What type of funding is this categorized as?
It is categorized as discretionary funding under science and technology and other research and development.
What funding instruments are available?
Funding instruments available include grants and cooperative agreements.
What is the difference between a grant and a cooperative agreement for this opportunity?
The listing indicates both grants and cooperative agreements may be used. This implies some awards could involve a more collaborative relationship with the government than a standard grant, depending on the specific terms of the award.
Who is eligible to apply?
Eligibility is listed as unrestricted, meaning a broad range of organizations could apply, subject to any additional eligibility language in the full announcement.
How many awards were expected?
The posting listed an expected number of awards of four.
When was the opportunity posted and when did it close?
The timeline shows a creation date of March 30, 2020, and an original closing date of July 29, 2020.
What was the award ceiling?
The posted award ceiling is shown as 0, which typically indicates the ceiling was not specified in that data field. The ceiling would need to be confirmed in the full funding announcement or accompanying program guidance.
Does the information provided specify the maximum award amount?
No. The award ceiling field is shown as 0 in the posting, which usually means it was not specified there. The maximum award amount would need to be verified in the full announcement materials.
What distinguishes this award from other research mechanisms?
A defining feature is its emphasis on patient-centric outcomes and clinically useful evidence from trials conducted in people. The opportunity prioritizes evidence that can improve real-world clinical decision-making and encourages pragmatic and practice-based research designs.
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