Comprehensive Alcohol-HIV/AIDS Research Center (P60 Clinical Trial Optional) | RFA AA 19 003

Opportunity Information: Apply for RFA AA 19 003

The Comprehensive Alcohol-HIV/AIDS Research Center (P60 Clinical Trial Optional) funding opportunity (RFA-AA-19-003) is a National Institutes of Health grant announcement led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports the creation or continuation of a coordinated research center focused on cross-cutting, multidisciplinary work at the intersection of alcohol use and HIV/AIDS. The main idea is to bring together multiple related projects under one center structure so the combined effort can tackle complex, real-world problems more effectively than isolated studies. While clinical trials are optional under this FOA, the expectation is that the overall research portfolio is organized, synergistic, and positioned to produce findings that can move toward practical impact.

The core purpose of the center is to generate knowledge that can be translated into interventions that reduce HIV infection and transmission, particularly in contexts where alcohol use contributes to risk. That translation focus is emphasized: NIAAA is looking for research that does not stop at describing associations, but instead helps drive better prevention, care, and implementation approaches. Applicants are expected to align their research priorities with the goals laid out in the FY2013 Trans-NIH Plan for HIV-Related Research, which is referenced as a framework for identifying high-priority directions across the federal HIV research enterprise. In practical terms, a competitive center application would typically be expected to show how its projects and shared resources collectively advance those priority goals and how the center will accelerate progress by coordinating expertise, populations, methods, and intervention development or testing.

This FOA is categorized as a discretionary grant opportunity within the health funding activity area (CFDA 93.273). The funding instrument is a grant, and the mechanism is a P60 research center grant, which generally implies an integrated set of projects supported by centralized cores (for example, administrative coordination, data management, biostatistics, clinical coordination, or community engagement resources) that enable the science to function as a cohesive program. Although the specific award ceiling and expected number of awards are not provided in the source text, the announcement includes a concrete application due date (original closing date of April 16, 2019) and a posting/creation date (December 11, 2018), indicating it was issued for a defined submission window.

Eligibility is broad and spans many types of U.S.-based organizations that can support substantial research programs. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional eligible applicant categories that NIH often encourages to participate, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also notes eligibility for faith-based or community-based organizations, regional organizations, and eligible agencies of the federal government, as well as U.S. territories or possessions, reinforcing that the program is intended to be accessible to a wide range of institutions that can credibly operate a multidisciplinary research center.

At the same time, the FOA draws clear boundaries around foreign participation. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply as the main applicant organization, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed. That means a U.S. applicant organization can, when justified, include certain foreign collaborations or research elements as part of the overall project structure, consistent with NIH policy, even though the applying institution itself must be domestic.

Overall, this opportunity is aimed at building a well-structured, center-based research program that connects alcohol research and HIV/AIDS research in a way that produces actionable outcomes. The emphasis on cross-cutting science and translation into interventions signals interest in integrated approaches that can reduce HIV acquisition and transmission risk where alcohol plays a role, and in center models that can coordinate multiple projects, shared infrastructure, and collaborative teams to move the field forward efficiently.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Comprehensive Alcohol-HIV/AIDS Research Center (P60 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
• This funding opportunity was created on 2018-12-11.
• Applicants must submit their applications by 2019-04-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AA 19 003

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