Opportunity Information: Apply for CDC RFA GH21 2123
This funding opportunity (CDC RFA GH21-2123) is a PEPFAR-supported cooperative agreement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), focused on strengthening South Africa's health information systems (HIS) through hands-on technical assistance. The overall intent is to help the South African National Department of Health (NDoH) and sub-national health authorities improve patient-level data systems by building and refining digital health platforms that can connect to each other and work as an integrated ecosystem. The emphasis is on making existing and future systems more useful for frontline care, program management, and decision-making by improving interoperability, data quality, and practical use of information across the health sector.
The core technical scope centers on developing and implementing digital platforms that allow different national and sub-national systems to exchange data reliably. The opportunity specifically highlights interoperability across clinical information systems, laboratory systems, demographic and patient registry-type capabilities (including HPRS), program monitoring platforms (including WebDHIS), differentiated service delivery systems, mHealth tools, and other related systems and subsystems. In plain terms, the work is meant to reduce fragmentation so that patient information and program data can be linked and used across services and levels of care, rather than sitting in disconnected databases that do not communicate. By improving how these systems connect, the CDC expects stronger continuity of care, better monitoring of patient outcomes, and more accurate reporting and planning at facility, district, provincial, and national levels.
Recipients are expected to operate in close partnership with the South African government rather than working independently. A key requirement is alignment with NDoH policies and national digital health strategy objectives, with active coordination among the NDoH, Provincial Departments of Health (PDoH), and other health information system stakeholders and district support partners (DSPs). The award focuses on organizing, supporting, and accelerating the development, implementation, and scale-up of HIS integration efforts across South Africa, including improving existing systems so that integrated data can actually be used for patient-centered service delivery and for management decisions. Sustainability is explicitly called out, meaning the technical assistance should help government institutions adopt approaches that can be maintained long term at all levels of the health system, rather than creating solutions that depend permanently on external implementers.
A major expected outcome area is improved data quality and stronger data use. The technical assistance is intended to make patient-level information more reliable and actionable, which supports higher-quality, patient-centered healthcare services and enables better planning and resource allocation. This includes supporting the ability of the HIS to generate usable insights for program improvement, routine management, and strategic decisions, reflecting a shift from data collected mainly for reporting to data actively used to guide services and policy.
The opportunity also expects ongoing monitoring of progress through process and outcome evaluation checks. In practice, this means recipients should establish ways to track whether the technical support is actually leading to measurable improvements in system integration, usability, and performance against the NOFO's expected outcomes, and then use those findings to adjust implementation.
From a funding and administrative standpoint, the award instrument is a cooperative agreement, which typically implies substantial involvement and collaboration with CDC during implementation. The funding activity category is Health, and the CFDA/Assistance Listing number is 93.067. Eligibility is listed as unrestricted (open to any type of entity, subject to any additional eligibility clarifications in the full notice). CDC anticipated making two awards. For budgeting, the notice states that the Year 1 award ceiling is listed as 0 (none), while CDC anticipated an approximate total fiscal year funding amount of $5,000,000 for Year 1, contingent on funds being available. The opportunity was created March 3, 2021, with an original closing date of May 2, 2021, and required electronic submission by 11:59 pm ET on the due date.
Overall, this NOFO is essentially a targeted investment in the technical capacity, governance alignment, and practical implementation support needed for South Africa to run more integrated, interoperable, and sustainable health information systems that strengthen patient-level data and improve how data is used to deliver and manage health services under PEPFAR-supported objectives.Apply for CDC RFA GH21 2123
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Technical Assistance (TA) to Support the Health Information Systems (HIS) of the South African Government to Improve Patient-level Data Systems at the National and Sub-National Departments of Health (DoH) under PEPFAR" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Mar 03, 2021.
- Applicants must submit their applications by May 02, 2021 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)
1) What is CDC RFA GH21-2123?
CDC RFA GH21-2123 is a PEPFAR-supported funding opportunity from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC). It is issued as a cooperative agreement focused on strengthening South Africa's health information systems (HIS) through hands-on technical assistance.
2) What is the main goal of this cooperative agreement?
The main goal is to help the South African National Department of Health (NDoH) and sub-national health authorities improve patient-level data systems by building and refining digital health platforms that connect to each other as an integrated ecosystem. The emphasis is on interoperability, data quality, and practical use of information for frontline care, program management, and decision-making.
3) What does "hands-on technical assistance" mean in this opportunity?
Based on the description, hands-on technical assistance refers to active, practical support that helps organize, accelerate, develop, implement, and scale up HIS integration efforts across South Africa, rather than working independently or only producing high-level recommendations.
4) What kinds of systems are expected to be included in the interoperability work?
The opportunity highlights interoperability across clinical information systems, laboratory systems, demographic and patient registry-type capabilities (including HPRS), program monitoring platforms (including WebDHIS), differentiated service delivery systems, mHealth tools, and other related systems and subsystems.
5) What problem is the NOFO trying to solve within South Africa's HIS environment?
It is aimed at reducing fragmentation where patient information and program data sit in disconnected databases that do not communicate. The goal is to enable reliable data exchange so information can be linked and used across services and levels of care.
6) What outcomes does CDC expect from improved interoperability?
The NOFO links improved interoperability to stronger continuity of care, better monitoring of patient outcomes, and more accurate reporting and planning at facility, district, provincial, and national levels.
7) Is this opportunity focused on building entirely new systems or improving existing ones?
It is focused on strengthening patient-level data systems by building and refining digital health platforms, and it explicitly includes improving existing systems so that integrated data can actually be used for patient-centered service delivery and management decisions.
8) How closely must recipients work with the South African government?
Recipients are expected to operate in close partnership with the South African government rather than working independently. A key requirement is alignment with NDoH policies and national digital health strategy objectives, with active coordination among NDoH, Provincial Departments of Health (PDoH), and other HIS stakeholders and district support partners (DSPs).
9) What does alignment with NDoH policies and strategy imply for implementation?
The NOFO indicates that technical work should be consistent with NDoH policies and national digital health strategy objectives, and that implementation should be coordinated with relevant national and sub-national actors rather than being a parallel effort.
10) What does "sustainability" mean in the context of this award?
Sustainability is explicitly emphasized as technical assistance that helps government institutions adopt approaches that can be maintained long term at all levels of the health system, rather than creating solutions that depend permanently on external implementers.
11) What is the role of data quality in this opportunity?
Improved data quality is a major expected outcome area. The technical assistance is intended to make patient-level information more reliable and actionable to support higher-quality, patient-centered healthcare services and enable better planning and resource allocation.
12) What is meant by "stronger data use" in this NOFO?
The NOFO describes a shift from data collected mainly for reporting to data actively used to guide services and policy. The HIS should be able to generate usable insights for program improvement, routine management, and strategic decisions.
13) Does the opportunity require monitoring and evaluation of progress?
Yes. The opportunity expects ongoing monitoring of progress through process and outcome evaluation checks. Recipients should establish ways to track whether technical support leads to measurable improvements in system integration, usability, and performance against expected outcomes, and then use findings to adjust implementation.
14) What type of award instrument is this?
The award instrument is a cooperative agreement, which typically implies substantial involvement and collaboration with CDC during implementation.
15) What is the funding activity category?
The funding activity category is Health.
16) What is the CFDA/Assistance Listing number for this opportunity?
The CFDA/Assistance Listing number is 93.067.
17) Who is eligible to apply?
Eligibility is listed as unrestricted, meaning it is open to any type of entity, subject to any additional eligibility clarifications that may be included in the full notice.
18) How many awards did CDC anticipate making?
CDC anticipated making two awards.
19) What was the anticipated funding level for Year 1?
The notice indicates an approximate total fiscal year funding amount of $5,000,000 for Year 1, contingent on funds being available.
20) Why does the notice show a Year 1 award ceiling of 0?
The information provided states that the Year 1 award ceiling is listed as 0 (none), while also stating an anticipated approximate total fiscal year funding amount of $5,000,000 for Year 1 (contingent on funds being available). The provided text does not explain the reason for this discrepancy.
21) When was this opportunity created and when did it close?
The opportunity was created on March 3, 2021. The original closing date was May 2, 2021.
22) What were the submission requirements and deadline time zone?
The NOFO required electronic submission by 11:59 pm ET on the due date.
23) What geographic focus does this opportunity target?
The work described is focused on South Africa, supporting national and sub-national health authorities, including NDoH and Provincial Departments of Health.
24) What is the practical end result CDC is looking for?
The NOFO describes a targeted investment in technical capacity, governance alignment, and practical implementation support so South Africa can run more integrated, interoperable, and sustainable HIS that strengthen patient-level data and improve how data is used to deliver and manage health services under PEPFAR-supported objectives.
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